规格
Accession Number:	NP_000213, T670I
Assay Entry:	Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Protein Form:	Recombinant, Cytoplasmic
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry:	KIT T670I
Target Gene:	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Gene ID (Entrez):	3815, 9586
Molecular Weight:	53.3 kDa
Protein Subtype:	Receptor Tyrosine Kinases
Gene Alias:	KIT T670I, cKit, PBT
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	PDGFR Kinase Family
Protein Length:	aa 544-976; T670I
Protein Tag:	His Tag

储存
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.

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