规格
Accession Number:	BC054510.2
Assay Entry:	Cell-based beta lactamase reporter gene
Cell Line:	293T (HEK)
Cell State:	Dividing Cells
Druggable Target:	GPCRs
Gene Symbol:	HRH2
Population Status:	Single Cell Clone Origin
Product Line:	GeneBLAzer®
Reporter Gene:	BLA (Beta-Lactamase)
System Type:	GeneBLAzer™
Target Entry:	HRH2, H2
Technique:	FRET
Detection Method:	Fluorescent

储存

Contents:
K1707 GeneBLAzer® H2-CRE-bla HEK293T cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® H2-CRE-bla HEK293T cells
• GeneBLAzer® H2-CRE-bla HEK293T Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer® H2-CRE-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

描述

GeneBLAzer® H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor® CRE-bla HEK293T cell line. CellSensor® CRE-bla HEK293T cells (Cat. no. K1540) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer® H2-CRE-bla HEK293T cells are functionally validated for Z' and EC₅₀ concentrations of Histamine. In addition, GeneBLAzer® H2-CRE-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The H2 receptor has been implicated in a number of disorders, including peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), dyspepsia, and stress ulcer prophylaxis.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

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