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AMPK (A1/B2/G1) 100 ug,PV6245,赛默飞世尔

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订货号 1EX1548
品牌型号 赛默飞世尔 PV6245
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Kinase Group: Serine/Threonine Kinase
Species: Human
Molecular Weight: 63.6/36/40 kDa
Validated Application: Kinase Assay
Protein Length: aa 10-end
Protein Tag: His Tag
储存
Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
描述

AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The beta subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle. Recombinant full-length human AMPK (combination of A1/B2/G1 subunits) was expressed by baculovirus in Sf9 insect cells using a C-terminal His tags.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

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