规格
Accession Number:	NM_033439
Bioassay:	Proliferation of Mouse D10S Cells
Endotoxin Level:	< 0.1 ng/µg
Mass:	10 µg
Product Line:	Gibco®
Purity or Quality Grade:	Carrier-Free
Reactivity:	Human
Shipping Condition:	Wet Ice
Specific Activity:	1.0 x 10⁷ - 1.0 x 10⁶ units⁄mg
Expression System:	E. coli
Form:	Lyophilized
Protein Family:	Cytokines & Receptors
Protein Form:	Recombinant, Ligand
Protein Subtype:	Interleukins
Research Category:	Cell Cycle & Proliferation, Signal Transduction
Species:	Human
Validated Application:	Cell Culture
Gene ID (Entrez):	90865
Molecular Weight:	18 kDa
Purification Method:	Sequential Chromatography
Purity:	95 %
Quantity:	10μg
Gene Alias:	IL-33
Gene Symbol:	IL33
Protein Length:	159 aa
Biological Activity:	ED₅₀ range = 0.1-1.0 ng⁄mL

储存
Lyophilized Human IL-33 should be stored at 2-8°C, preferably desiccated. Store reconstituted Human IL-33 at ≤ –20°C (not in a frost-free freezer). Keep freeze-thaw cycles to a minimum. Please look at all pack sizes when trying to fill an order.

描述

Recombinant IL33 is a bioactive protein intended for use in cell culture applications. IL33 is a proinflammatory cytokine with structural homology similar with IL-1 family cytokines. IL33 exerts its biological effects by binding to the receptor ST2 and forming a complex with IL-1 Receptor Accessory Protein. Intracellular proteins within in the NF-κB and MAP kinase signaling pathways are activated leading to the production of the type 2 cytokines IL-5 from polarized TH2 cells.

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