规格
Accession Number:	NP_741960
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Ser⁄Thr Kinases: CAMK Group
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	CAMK2A
Target Gene:	calcium⁄calmodulin-dependent protein kinase (CaM kinase) II alpha
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant
Protein Subtype:	Serine⁄Threonine Kinases
Research Category:	Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	25400, 815, 816, 817, 818
Molecular Weight:	56.8 kDa
Gene Alias:	CAMK2A (CaMKII Alpha)
KinaseFamily:	CAMK2 Kinase Family
Protein Tag:	His Tag

储存
Storage Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 0.5 mM EDTA, 0.05% NP-40, 2 mM DTT and 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

CAMK2A (CaMKII alpha) is a serine⁄threonine kinase that regulates a number of cellular functions including neuronal processes, gene expression, carbohydrate metabolism, cytoskeletal function, and calcium homeostatsis. Autophosphorylation of threonine 286 in the presence of Ca2+ and calmodulin activates CAMK2A with the ability to switch from calmodulin-dependent to a calmodulin independent activity.

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