规格
Accession Number:	NP_775869
Shipping Condition:	Dry Ice
Expression System:	Insect
Protein Form:	Recombinant, Active, Catalytic
Validated Application:	Kinase Assay
Molecular Weight:	72.1 kDa
KinaseFamily:	MAP Kinases
Protein Length:	aa 544 - end
Protein Tag:	GST Tag

储存
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

描述

This KSR2 recombinant human protein (554–end) was expressed in insect cells. KSR2 serine/threonine kinase or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family. KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf molecule in trans. KSR2 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

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