Host species | Rabbit |
Species reactivity | |
Immunogen | Ramucirumab |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
Clonality | Polyclonal |
Isotype | IgG |
Applications | ELISA |
Target | |
Purification | Antigen affinity purification. |
Stability and Storage | The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
Background | Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells. |
Alternative Names | Rabbit polyclonal to REGN-10987. |
Note | Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only. |