Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
Detection method | Colorimetric |
Sample type | Plasma, Serum |
Assay type | Quantitative |
Sensitivity | 0.156 μg/ml |
Range | 0.31-5 μg/mL |
Recovery | 80-120% |
Background | Ifabotuzumab (formerly KB004) is a first-in-class therapeutic non-fucosylated IgG1 (human f-allotype) monoclonal antibody being developed by Humanigen (formerly KaloBios Pharmaceuticals) for the treatment of cancer. The drug was licensed from the Ludwig Institute for Cancer Research. The molecule contains a human antibody constant region with V-regions that are 92% identical to human germ-line sequences. Ifabotuzumab targets the ephrin type-A receptor 3 (EphA3) tyrosine kinase. In non-clinical studies, Ifabotuzumab demonstrated potent ex-vivo cell killing of EphA3+ tumor cells obtained from patients with hematologic malignancies. |
Alternative Names | Fibatuzumab, KB-004, , CAS: 1234137-51-9 |
Shipping | 2-8 ℃ |
Specifications | Ifabotuzumab |
Note | For Research Use Only. |