PRKCA (PKC ALPHA) RHUMAN 10UG EA，A41891，Applied Biosystems

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订货号： 0AE1621

品牌型号： Applied Biosystems A41891

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产品介绍 Product Description

规格
Accession Number:	NP_002728.1
Shipping Condition:	Dry Ice
Expression System:	Insect
Protein Form:	Full Length, Active
Research Category:	Drug Development
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	PRKCA
Molecular Weight:	110.0 kDa
Gene Alias:	PKCA, PKC-A, PRKACA
KinaseFamily:	PKC Kinase Family
Protein Tag:	GST Tag

储存
Storage Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

The PKC family of serine/threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.

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